transoceanic scoreline: September 2012

Thursday, September 20, 2012

Quayle on Fast and Furious report: Holder ?lied to my face? during House testimony

Arizona Republican Rep. Ben Quayle told The Daily Caller that Attorney General Eric Holder intentionally gave him false testimony under oath about Operation Fast and Furious wiretap application documents during a June 7 House Judiciary Committee hearing.

Quayle said the Department of Justice?s inspector general report proves that Holder lied to him while under oath during the hearing.

?I saw earlier that Holder is basically doing a victory dance and that he thinks this [inspector general] report exonerates him and there was no dishonesty with Congress ? that?s just a blatant lie,? Quayle said in a phone interview. ?I mean, he lied to me ? to my face ? during questioning, saying they had reviewed the wiretap applications after the fact and claiming that there was no reference to gunwalking, which is blatantly false.?

Holder told Quayle during congressional questioning that wiretap application affidavits and summaries from Fast and Furious did not, upon his review, mention anything about gunwalking that would have raised the concerns of senior Justice Department officials who signed and approved them.

?I?ve looked at these affidavits. I?ve looked at these summaries. There?s nothing in those affidavits as I?ve reviewed them that indicates gunwalking was allowed,? Holder said during the hearing. ?Let?s get to the bottom line. I didn?t see anything in there that would put on notice a person who was reviewing either at the line level or at the Deputy Assistant Attorney General level, that you would have knowledge of the fact that these inappropriate tactics were being used.?

Quayle followed up by asking: ?Are you saying in the summaries or in the whole affidavit??

Holder confirmed that his statement was about ?in the summary as well as in the affidavit.?

The DOJ inspector general came to the opposite conclusion about those very same affidavits, essentially implying that that Holder statement is not true.

?We reviewed the wiretap affidavits in both Operation Wide Receiver and Operation Fast and Furious and concluded that the affidavits in both cases included information that would have caused a prosecutor who was focused on the question of investigative tactics, particularly one who was already sensitive to the issue of ?gun walking,? to have questions about ATF?s conduct of the investigations,? the inspector general wrote in its report released Wednesday.

If House members were to pursue perjury charges against Holder for this apparently false statement to Congress, they would likely run into the same roadblock they encountered in holding Holder in criminal contempt of Congress. (RELATED: Key Holder deputy resigns as inspector general releases Fast and Furious report)

This summer, a bipartisan group of House members voted Holder into both criminal and civil contempt of Congress for his failure to comply with a congressional subpoena into Fast and Furious. The criminal contempt resolution stalled because Holder?s DOJ told Ron Machen, the U.S. Attorney for the District of Columbia, not to enforce it.

House members, however, remain intent on pursing the civil contempt charges in court ? with the ultimate goal of having a federal judge overturn President Barack Obama?s use of executive privilege to help Holder withhold Fast and Furious documents.

DOJ spokeswoman Tracy Schmaler has not responded to TheDC?s request for comment about this apparent lie Holder made before the House Judiciary Committee.

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Ashbel Green, editor of Cronkite, dies at age 84

NEW YORK (AP) ? Ashbel Green, a versatile and respected editor at Alfred A. Knopf who persuaded Gabriel Garcia Marquez to switch publishers, worked on Walter Cronkite's memoir and a foreign policy book by President George H.W. Bush and helped discover the crime classic "The Friends of Eddie Coyle," has died. He was 84.

The publisher announced Wednesday that Green died Tuesday night while dining with his wife, Elizabeth Osha, near their home in Stonington, Conn. The cause of death was not immediately given.

Known to his friends as "Ash," Green was an old-school publishing man who preferred a typewriter to computers and was praised by The New York Observer as "an exemplar of elegance, decency and seriousness." Green acquired and edited hundreds of books and as managing editor at Knopf looked through the endless unsolicited manuscripts known as the "slush pile."

"Ash was a prodigious talent, one of the most significant editorial figures in modern publishing, famous for his breadth of reading and grasp of history," Knopf president Sonny Mehta said in a statement. "Many of us had the good fortune of learning a great deal about the business from him. He was a beloved colleague, and his contributions to our company ? an esteemed editorial legacy ? are part of what still define us today."

The son of a newspaperman and descendant of Presbyterian ministers, Green was born in New York in 1928. He graduated from Columbia College in 1950 and two years later received a master's in Eastern European history from Columbia. He worked as publicity director of Prentice Hall, developed a love for editing and was hired by Knopf in 1964 as managing editor. Nine years later, he was promoted to vice president and senior editor and remained in those positions until his retirement, in 2007.

In the early 1970s he came upon a story about the Irish-American underworld in Boston, written by an Assistant U.S. Attorney General George V. Higgins. Although put off by the two-page cover letter ? "George sometimes tended to garrulity," Green later told the alumni publication Columbia Magazine ? he looked through the submission, liked it and paid $2,000 for a novel now considered a masterpiece and made into a film starring Robert Mitchum.

At an elite publishing house that included literary editor Gary Fisketjon and poetry editor Harry Ford, Green had a special interest in politics and history. He edited the Pulitzer Prize-winning "Founding Brothers" by Joseph Ellis, who in the introduction cited Green's reputation as "the salt of the earth." He acquired many works by Cold War dissidents, among them Andrei Sakharov's memoir and books by Milovan Djilas and Vaclav Havel.

Green's other projects included Cronkite's "A Reporter's Life" and a collaboration between Bush and former National Security Adviser Brent Scowcroft titled "A World Transformed." He also worked with historians Ken Burns and Geoffrey Ward and the novelists Ernest J. Gaines and Winston Groom.

A notable achievement was getting Garcia Marquez to join Knopf in the 1980s after a long history with Harper & Row (now HarperCollins). According to Al Silverman's "The Time of Their Lives," a publishing history, Green had heard that negotiations were stalled for Garcia Marquez's novella "Chronicle of a Death Foretold." Green contacted the Nobel laureate's agent, noted Knopf's history of publishing Latin American authors and acquired the English edition of his new book and many of his older ones.

Green's job required patience and firmness, especially when dealing with the famous. He waited years for Cronkite to finish his book and had to prod Bush and Scowcroft.

Barbara Bush, the former first lady, wrote in her memoir that her husband and his close friend "were the most reluctant of writers. I had loved writing my memoirs in contrast to those two, who suffered." Finally, Green and other Knopf executives arrived at the Bush home in Houston and urged them to "get on with it!"

Source: http://news.yahoo.com/ashbel-green-editor-cronkite-dies-age-84-145507329.html

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Tuesday, September 18, 2012

There?s another passion behind the music of Whitehorse: The sound of scientific thinking

There?s another passion behind the music of Whitehorse: The sound of scientific thinking | Guest Blog, Scientific American Blog Network '); } else { $('#'+formID+' > .error').fadeOut('slow'); $('#'+formID+' > .error').html(json.MESSAGE); } $('#'+formID+' > .error').fadeIn('slow'); } else { $('#'+formID).hide(); $('#'+formID).after('

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Libya sacks Benghazi security chiefs after US attacks

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Source: http://news.yahoo.com/libya-sacks-benghazi-security-chiefs-us-attacks-153341534.htmlrick santorum daughter gainesville 2012 royal rumble the grey machine gun kelly saul alinsky annapolis

Monday, September 17, 2012

We're live from Photokina 2012 in Cologne, Germany!

Germany just can't get enough of Engadget, it seems. Just two weeks after the close of IFA in Berlin, we're back in the land of Bier and Honig, for a camera-fueled journey to Cologne. This giant photography trade show is held only once every two years -- the last Photokina was way back in 2010 -- and it's arguably the industry's biggest event, drawing manufacturers the world abound to launch their latest prosumer and professional devices. We won't likely see a blockbuster product like Samsung's Galaxy Camera, but there could be another Android shooter or two in store, along with plenty of updates to last year's advanced compacts and mirrorless cams, and a modest spattering of full-frame DSLRs. We'll be bringing you all the news as it happens, so keep your eyes peeled to this very site to catch the action as it goes down.

Gallery: We're live from Photokina 2012

Filed under: Announcements, Cameras

We're live from Photokina 2012 in Cologne, Germany! originally appeared on Engadget on Mon, 17 Sep 2012 09:00:00 EDT. Please see our terms for use of feeds.

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Where Does She Go to Regain Her Reputation? Will the Prosecution Be Punished? (Theagitator)

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Friday, September 14, 2012

BlackBerry Updates Facebook App to Support Birthday, Event Alerts

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Source: http://news.yahoo.com/blackberry-updates-facebook-app-support-birthday-event-alerts-120123450.html

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Scientists Discover How an Out-of-Tune Protein Leads to Muscle Demise in Heart Failure

ScienceDaily (Sep. 12, 2012) ? A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.

Troponin I, found exclusively in heart muscle, is already used as the gold-standard marker in blood tests to diagnose heart attacks, but the new findings reveal why and how the same protein is also altered in heart failure. Scientists have known for a while that several heart proteins -- troponin I is one of them -- get "out of tune" in patients with heart failure, but up until now, the precise origin of the "bad notes" remained unclear.

The discovery, published online ahead of print on Sept. 12 in the journal Circulation, can pave the way to new -- and badly needed -- diagnostic tools and therapies for heart failure, a condition marked by heart muscle enlargement and inefficient pumping, and believed to affect more than 6 million adults in the United States, the researchers say.

Troponin I acts as an on-off switch in regulating heart relaxation and contraction and, in response to, adrenaline -- the "flight-fight" response. But when altered, troponin I can start acting as a dimmer switch instead, one that ever so subtly modulates cardiac muscle function and reduces the heart's ability to pump efficiently and fill with blood, the researchers found.

The Hopkins team used a novel method to pinpoint the exact sites, or epicenters, along the protein's molecule where disease-triggering changes occur. They found 14 such sites, six of them previously unknown. In revealing new details about the molecular sequence of events leading up to heart failure, the researchers said their work may spark the development of tests that better predict disease risk and monitor progression once the heart begins to fail.

"Our findings pinpoint the exact sites on troponin I's molecule where disease-causing activity occurs, and in doing so they give us new targets for treatment," says researcher Jennifer Van Eyk, Ph.D., director of the Johns Hopkins Proteomics Innovation Center in Heart Failure.

In the current study, the team analyzed tissue from the hearts of patients with end-stage heart failure and from deceased healthy heart donors. The 14 sites the researchers identified are sites where troponin I binds with phosphate, a process known as phosphorylation.

Phosphate can activate or deactivate many enzymes, thus altering the function of a protein and, in the case of heart failure, ignite disease. The six newly identified sites represent new "hot spots" involved in heart contraction, the researchers say, and could be used as diagnostic markers or a target for treatment to restore function.

The Hopkins researchers found that in some sections of the molecule, phosphorylation ratcheted up the dimmer switch, while ratcheting it down in other sections, but it invariably led to muscle dysfunction.

"Our goal would be to zero in on these new sites, gauge risk of heart failure and, hopefully, restore heart muscle function," Van Eyk says.

Heart failure is a complex progressive disorder, and while cardiac pacemakers can restore or "resynchronize" heart function in many people, about one-third of patients do not improve even with pacemaker therapy in addition to standard medication treatments.

"This is a devastating disorder for which we desperately need new and less invasive therapies," says senior investigator Anne Murphy, M.D., a cardiologist at Johns Hopkins Children's Center.

In their analysis, the researchers used a novel technique, called multiple-reaction monitoring (MRM), which pinpoints the exact locations along the protein's molecule where faulty signaling occurs and disrupts heart muscle function. MRM is an ultra-sensitive type of mass spectrometry that measures the exact size and chemical composition of protein fragments. Phosphorylated protein fragments have different molecular weights than non-phosphorylated ones. In this way, MRM accurately homes in on sites where phosphate is bound to troponin I to modulate heart muscle function.

The researchers found that patients with heart failure had markedly different levels of phosphorylation in certain protein segments compared with healthy heart muscle.

The advantage of MRM analysis -- one of the first non-antibody based troponin I tests -is that it can measure phosphorylation levels without the need for antibodies, the traditional method currently used to monitor heart muscle function. The researchers believe that MRM can be developed as a clinical diagnostic test, and the Hopkins team is already working to develop a test that would measure phosphorlyation levels of proteins in the blood and would allow physicians to monitor the progression of the disease as well as predict which heart attack patients will progress to heart failure. About one-third of them do so.

"Right now, we don't really know which heart attacks patients will develop heart failure and which ones will maintain normal heart muscle function," Murphy says. "Monitoring specific phosphorylation sites might be one way to help us foresee and forestall this complication on an individual patient basis."

Other Johns Hopkins investigators on the study included Pingbo Zhang, Ph.D., Weihua Ji, M.S., Cristobal G. dos Remedios, D.Sc., Jonathan Kirk, Ph.D., and David Kass, M.D.

This work was supported by the National Heart Lung and Blood Institute's Proteomic Initiative contracts NHLBI-HV-10-05(2) and HHSN268201000032C, P01HL081427, P01HL77189-01, and R01 HL63038; by the Johns Hopkins Clinical Translational Science Award (CTSA); and by American Heart Association Postdoctoral Fellowships 10POST4000001 and 11POST7210031.

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The above story is reprinted from materials provided by Johns Hopkins Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

P. Zhang, J. A. Kirk, W. Ji, C. G. dos Remedios, D. A. Kass, J. E. Van Eyk, A. M. Murphy. Multiple Reaction Monitoring to Identify Site-Specific Troponin I Phosphorylated Residues in the Failing Human Heart. Circulation, 2012; DOI: 10.1161/CIRCULATIONAHA.112.096388

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/VsbDQn3tsUc/120912161927.htm

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Sunday, September 9, 2012

iPadGuru: VEVO?s New iPad App Adds Personalized Playlists, Social Sharing & Continuous Playback http://t.co/JtxrkMEq

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Saturday, September 8, 2012

40% of U.S. Mobile Users Will Click an Unsafe Link This Year

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Source: http://news.yahoo.com/40-u-mobile-users-click-unsafe-090920053.html

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Sharp mortgages itself to the hilt just to keep going

Sharp has mortgaged its offices and factory buildings in order to raise the cash it needs to stay in business, according to Reuters. It's cut a deal with banks for nearly $2 billion in short-term credit secured on its assets -- including the factory that reportedly produces displays for the iPhone. Sharp had pinned its hopes on cash from Hon Hai, but the Chinese giant is apparently delaying the money with the aim of gaining more control over Sharp's business. In response, Sharp has pledged to send president Takashi Okuda to meet Hon Hai's Terry Gou in Taipei -- just as soon as it's scraped together the air-fare.

Filed under: Cellphones, Displays, Home Entertainment, HD, Mobile

Sharp mortgages itself to the hilt just to keep going originally appeared on Engadget on Thu, 06 Sep 2012 06:41:00 EDT. Please see our terms for use of feeds.

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Friday, September 7, 2012

MTV Video Music Awards: Who Were the Big Winners?

Rihanna beat her best friend Katy Perry for the top Moonman at the 2012 MTV Video Music Awards. The singer, who opened Thursday night's show with a sexy remix of her hit single "Cockiness," snagged the award for video of the year for her epic dance anthem "We Found Love."

Source: http://www.ivillage.com/mtv-video-music-awards-one-direction-rihanna-win/1-a-485297?dst=iv%3AiVillage%3Amtv-video-music-awards-one-direction-rihanna-win-485297

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Thursday, September 6, 2012

Sandra Fluke slams Romney over contraception at DNC

CHARLOTTE, N.C.--Recent law school graduate Sandra Fluke, who became a heroine on the left this year when she appeared at a Democratic hearing to argue for federal subsidies for contraception, spoke on Wednesday at the Democratic National Convention, where she suggested that Mitt Romney would restrict access to birth control if elected.

Fluke told the crowd that under Romney, the country could become a place "in which access to birth control is controlled by people who will never use it; in which politicians redefine rape so survivors are victimized all over again. ... We know what this America would look like. In a few short months, it's the America we could be."

Some of you may remember that earlier this year, Republicans shut me out of a hearing on contraception. In fact, on that panel, they didn't hear from a single woman, even though they were debating an issue that affects nearly every woman. Because it happened in Congress, people noticed. But it happens all the time. Many women are shut out and silenced. So while I'm honored to be standing at this podium, it easily could have been any one of you. I'm here because I spoke out, and this November, each of us must do the same.

During this campaign, we've heard about the two profoundly different futures that could await women?and how one of those futures looks like an offensive, obsolete relic of our past. Warnings of that future are not distractions. They're not imagined. That future could be real.

In that America, your new president could be a man who stands by when a public figure tries to silence a private citizen with hateful slurs. Who won't stand up to the slurs, or to any of the extreme, bigoted voices in his own party. It would be an America in which you have a new vice president who co-sponsored a bill that would allow pregnant women to die preventable deaths in our emergency rooms. An America in which states humiliate women by forcing us to endure invasive ultrasounds we don't want and our doctors say we don't need. An America in which access to birth control is controlled by people who will never use it; in which politicians redefine rape so survivors are victimized all over again; in which someone decides which domestic violence victims deserve help, and which don't. We know what this America would look like. In a few short months, it's the America we could be. But it's not the America we should be. It's not who we are.

We've also seen another future we could choose. First of all, we'd have the right to choose. It's an America in which no one can charge us more than men for the exact same health insurance; in which no one can deny us affordable access to the cancer screenings that could save our lives; in which we decide when to start our families. An America in which our president, when he hears a young woman has been verbally attacked, thinks of his daughters?not his delegates or donors?and stands with all women. And strangers come together, reach out and lift her up. And then, instead of trying to silence her, you invite me here?and give me a microphone?to amplify our voice. That's the difference.

Over the last six months, I've seen what these two futures look like. And six months from now, we'll all be living in one, or the other. But only one. A country where our president either has our back or turns his back; a country that honors our foremothers by moving us forward, or one that forces our generation to re-fight the battles they already won; a country where we mean it when we talk about personal freedom, or one where that freedom doesn't apply to our bodies and our voices.

We talk often about choice. Well, ladies and gentlemen, it's time to choose.

Source: http://news.yahoo.com/blogs/ticket/sandra-fluke-speaks-primetime-democratic-national-convention-022731441--election.html

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